Introduction to Pharmacokinetics and the factors affecting pharmacokinetic processes

Which other isozymes of Cytochrome P450 exhibit genetic polymorphism? For each case give an example of a drug that would normally be metabolised by each isozyme and the clinical implications of genetic polymorphism

Biochemical and behavioural Pharmacology

Experiment to determine the affinity for competitive antagonists at cholinoceptors in isolated tissues All the information is in the attached files. The first 3 files provide a description of what the experiment was about, how we carried it out, and theory etc. I have not been able to attach these files however, can email them on request. The calculations file are the calculations for the experiment and you need to use these to justofy results etc. What i want you to do is look at the attachment "write-up guideline" and provide a detailed solution and response to the RESULTS, DISCUSSION & A VERY BRIEF ADDITONAL SECTION areas.

Biochemical and behavioural Pharmacology

Experiment to determine the affinity for competitive antagonists at cholinoceptors in isolated tissues All the information is in the attached files. The first 3 files provide a description of what the experiment was about, how we carried it out, and theory etc. What i want you to do is look at the attachments and the following: INTRODUCTION: A brief indication of the aims of the experiment, a definition of competitive antagonism, and of the parameters investigated and an indication as to why it is important to be able to determine pA2, kA etc. Include an indication of which subtype of muscuranic receptor is present in the tissue and how it brings about its response when ac... click for more

Biochemical and behavioural Pharmacology

Hi, I have attached 2 calculations file. Using those calcuations, I am supposed to draw a log graph, However, I am totally clueless as to how I am supposed to proceed with it in regards to obtaining curves etc. Therefore, If somebody could start me off and give me an indiaction or explanation as to how I am supposed to draw the graph, I would be grateful. Thanks PS I know there is no log graph attached but if somebody could maybe draw a sample on word or other application it would be great.