What can you conclude about the gene(s) encoding VH and CH?

Recall that allelic forms of Ig constant regions exist. In the mouse, the locus encoding Ig heavy chain constant regions is named IgH. The inbred mouse strains BALB/c and C57BL/6 have different IgH alleles: BALB/c mice are IgHa and C57BL/6 mice are IgHb. They also differ in their humoral response to phosphorylcholine (PC). While both strains make equivalent amounts of PC-specific serum antibody, the response in BALB/c mice is dominated by antibodies with a VH region called "T15," which can be detected with an antiserum (anti-T15). In contrast, the PC-specific antibodies made by C57BL/6 mice don’t use the T15 VH. In the early 1970’s it was suggested that variable and constant regions were e... click for more

q2

2. The inbred mouse strains BALB/c and C57BL have different Ig heavy chain allotypes: The BALB/c allele is IgHa, whereas the C57BL allele is IgHb. C57BL mice make good immune responses to the antigen "Z", but BALB/c mice respond poorly. Assume you produced (BALB/c X C57Bl)F1 mice, then back-crossed these F1s to BALB/c. You tested 100 of the back-cross progeny for allotype(s) expressed in their serum, and for their ability to make anti-Z responses. The number of back-cross mice in each possible category are shown (Attached). A second experiment was done to further examine this intriguing "responder-non-responder" phenomenon. In this experiment, T and B cells from the two strains wer... click for more

Importance of Water

Life exists on Earth because of water. How does water contribute to the fitness of Earth to sustain life?

Ecosystem

1. What is an ecosystem? 2. What is ecology? 3. What are abiotic factors in the ecosystem? 4. What are biotic factors in the ecosystem? 5. Describe these types of organisms found in the ecosystem. Give an example of each a. producers b. herbivores c. carnivores d. omnivores e. detritivores f. decomposers REMEMBER: You are to compare two ecosystems. You are not expected to complete all the charts below. Choose the two that you studied, and leave the others blank. 6. Give the following information for the terrestrial ecosystem. (If you chose this one to study.) Supply as much information on the abiotic factors as possib... click for more

Prokaryotic and eukaryotic cells

Prokaryotic and eukaryotic cells share many similar features, developed and fine-tuned through years of evolution. Interestingly, the majority of prokaryotic cells exist as simple unicellular organisms, and only on rare occasions can grow together in colonies or demonstrate any type of intercellular communication. Eukaryotic cells, however, form the bodies of multicellular organisms and regularly produce specialized cells and structures. Identify and describe one or two structural and functional differences between prokaryotic and eukaryotic cells that you believe contribute to the ability of eukaryotic cells to form the specialized cells and structures found in multicellular organisms. ... click for more