Comparative Genomics

Comparative Genomics. See attached file for full problem description.

Mass Spec

Mass Spec. See attached file for full problem description.

siRNA

siRNA. See attached file for full problem description.

Haplotype

Haplotype. See attached file for full problem description.

Genetics/DNA Problems

You are studying a human disease that is inherited in an autosomal dominant fashion. You recognize that the disease maps to chromosome 10, so you obtain four DNA probes that hybridize to different chromosome 10 regions. A family in which the disease appears presents itself to a medical genetics clinic. DNA is extracted from each family member shown, cut with a restriction enzyme and tested on a Southern blot with each probe. 1a) Which probe would be most useful for your studies and for genetic counseling? Explain. 1b) Does the DNA probe that you selected in part a) actually include the disease gene? Explain. 1c) What is unusual about individual #7? What is the most likely explanat... click for more