Free Energy

Free Energy changes in glycolysis. a) Which three reactions are irreversible? What does this mean? b) The other seven reactions are near equilibrium. Explain how this diagram reflects this. Please see attached for full question.

Solution

In solution, 80% of the fructose 6-phosphate is in the beta-anomeric form and 20% is in the alpha-anomeric form... Please see attached for full question. It shoud be 2,5 -Anhydro..............(in beta configuration)

I need the answer for this question.

1. The energies of glycolysis shows that there is a large drop in free energy upon oxidation of glycerladehydes 3-phosphate to 1,3-bisphosphoglycerate. in the presence of oxygen, some of this energy is ultimately converted into ATP production. However, no such conversion happens under anaerobic conditions. Explain why? 2. How does the nonpolar nature of the active site in hexokinase promote phosphoryl transfer from ATP? 3. delta G knot for the aldolase reaction is 22.8 Kj/mol. In the cell at 37degree C, [DHAP]/[GAP]=5.5. Calculate the equilibrium ratio of [FBP]/[GAP] when [GAP]=10 to the power -4 M. 4. 2-phosphoglycerate and phosphoenolpyruvate differ only by dehydration between C-... click for more

enzyme superoxide dismutase and electrostatic potential

SOD is a diffusion-limited enzyme. What does it mean by "diffusion-limited enzyme"? Why will enzyme has electrostatic potential? Where are they from? What's the probable use of the enzyme's electrostatic potential? Is this enzyme related to metabolic pathway? If you have the suggest reading, please give me the link.

Biochem

1. The disease beriberi, which results from a dietary deficiency of vitamin B1 (Thiamine) is characterized by neurologic and cardiac symptoms, as well as increased levels of pyruvate and alpha- ketoglutarate in the blood. How does a deficiency of thiamine account for the increased levels of pyruvate and alpha- ketoglutarate? 2. Patients in shock experience decreased delivery of oxygen to tissues, decreased activity of the pyruvate dehydrogenase complex, and increased anaerobic metabolism. Excess pyruvate is converted to lactate, which accumulates in tissues and in the blood, causing lactic acidosis. a. Since oxygen is not a reactant or a product in the citric acid cycle, why do low ... click for more